This question has come up before and its hilarious -- NO women would beat Roddick on clay. Not even a chance. No matter the surface, the Men's game is just a completely different animal.
well a women has beaten a man in tennis. not sure when or who, but i heard that a male tennis player mocked women's tennis, and then a women challenged him and beat him in a match. I even heard stefi graff beat agassi
I think a better question would be who would win between roddick and venus williams. Roddick has a hard time returning serves and Venus' serve hit 129 i believe in this past final which is the same as most men.