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American League · National League
| Free Agents | Pos. | Status | | Julio Franco | 1B/3B | |
| Arbitration-Eligible | Pos. | Status | | Matt Diaz | OF | Re-signed ($1.225M, 1 year) | | Mike Gonzalez | LHP | Re-signed ($2.36M, 1 year) | | Rafael Soriano | RHP | Re-signed ($9M, 2 years) | | Mark Teixeira | 1B | Re-signed ($12.5M, 1 year) | | Tyler Yates | RHP | Re-sgned ($800K, 1 year) |
| Acquired | Pos. | Status | | Josh Anderson | OF | Traded from HOU | | Joe Borchard | RF | Signed (minor league deal) | | Jorge Campillo | RHP | Signed (minor league deal) | | Matt DeSalvo | RHP | Signed (minor league deal) | | Chase Fontaine | INF | Traded from TB | | Tom Glavine | LHP | Signed with ATL ($8M, 1 year) | | Omar Infante | UTL | Traded from CHC ($1.4M, 1 year) | | Jair Jurrjens | RHP | Traded from DET | | Mark Kotsay | CF | Traded from OAK | | Javy Lopez | C | Signed (minor league deal) | | Will Ohman | LHP | Traded from CHC | | Chris Resop | RHP | Claimed off waivers from ANA | | Jeff Ridgway | LHP | Traded from TB |
| Departed | Pos. | Status | | Willy Aybar | 3B | Traded to TB | | Jose Ascaino | RHP | Traded to CHC | | Lance Cormier | RHP | Signed with BAL (minor league deal) | | Octavio Dotel | RHP | Signed with CHW ($11M, 2 years) | | Joey Devine | RHP | Traded to OAK | | Willie Harris | OF | Signed with WAS ($800K, 1 year) | | Andruw Jones | CF | Signed with LA ($36.2M, 2 years) | | Pete Orr | UTL | Signed with WAS (minor league deal) | | Ron Mahay | LHP | Signed with KC ($8M, 2 years) | | Chad Paronto | RHP | Signed with HOU (1 year) | | Edgar Renteria | SS | Traded to DET | | Sergio Valenzuela | RHP | Selected by CIN in Rule 5 draft | | Oscar Villarreal | RHP | Traded to HOU | | Craig Wilson | RF | Signed with CIN (minor league deal) | | Chris Woodward | INF | Signed with NYY (minor league deal) |
| Free Agents | Pos. | Status | | Matt Herges | RHP | Re-signed ($2.5M, 1 year) | | Rodrigo Lopez | RHP | | | Ramon Ortiz | RHP | | | Mark Redman | LHP | Re-signed (1 year) | | Yorvit Torrealba | C | Re-signed ($7M, 2 years) |
| Arbitration-Eligible | Pos. | Status | | Garrett Atkins | 3B | Re-signed ($4.387M, 1 year) | | Brad Hawpe | RF | Re-signed ($3.925M, 1 year) | | Matt Holliday | LF | Re-signed ($23M, 2 years) | | Willy Taveras | CF | Re-signed ($1.975M, 1 year) | | Brian Fuentes | LHP | Re-signed ($5.05M, 1 year) |
| Acquired | Pos. | Status | | Jose Capellan | RHP | Traded from DET | | Marcus Giles | 2B | Signed (minor league deal) | | Scott Podsednik | OF | Signed (minor league deal) | | Josh Towers | RHP | Signed ($1.8M, 1 year) | | Luis Vizcaino | RHP | Signed ($7.5M, 2 years) | | Kip Wells | RHP | Signed ($3.1M, 1 year) | | Victor Zambrano | RHP | Signed (minor league deal) |
| Departed | Pos. | Status | | Jeremy Affeldt | LHP | Signed with CIN ($3M, 1 year) | | Denny Bautista | RHP | Traded to DET | | Jamey Carroll | 3B | Traded to CLE | | Elmer Dessens | RHP | Signed with PIT (minor league deal) | | Josh Fogg | RHP | Signed with CIN ($1M, 1 year) | | LaTroy Hawkins | LHP | Signed with NYY ($3.75M, 1 year) | | Jorge Julio | RHP | Signed with CLE (minor league deal) | | Tom Martin | LHP | Signed with LA (minor league deal) | | Kazuo Matsui | 2B | Signed with HOU ($16.5M, 3 years) | | Steven Register | RHP | Selected by NYM in Rule 5 draft |
| Free Agents | Pos. | Status | | Brad Ausmus | C | Re-signed ($2M, 1 year) | | Brian Moehler | RHP | Re-signed (minor league deal) | | Orlando Palmeiro | OF | |
| Arbitration-Eligible | Pos. | Status | | Brandon Backe | RHP | Re-signed ($800K, 1 year) | | Dave Borkowski | RHP | Re-signed ($800K, 1 year) | | Geoff Geary | RHP | Traded from PHI ($1.125, 1 year) | | Mark Loretta | INF | Re-signed ($2.75M, 1 year) | | Jose Valverde | RHP | Traded from ARI ($4.7M, 1 year) | | Ty Wigginton | 3B | Re-signed ($4.35M, 1 year) |
| Acquired | Pos. | Status | | Reggie Abercrombie | OF | Claimed off waivers from FLA | | Geoff Blum | INF | Signed ($1.1M, 1 year) | | Michael Bourn | LF | Traded from PHI | | Doug Brocail | RHP | Signed ($2.5M, 1 year) | | Jack Cassel | RHP | Signed ($400K, 1 year) | | Shawn Chacon | RHP | Signed ($2M, 1 year) | | Jose Cruz | OF | Signed (minor league deal) | | Darin Erstad | OF/INF | Signed ($1M, 1 year) | | Kevin Hooper | 2B | Signed (minor league deal) | | Kazuo Matsui | 2B | Signed ($16.5M, 3 years) | | David Newhan | LF | Signed (minor league deal) | | Chad Paronto | RHP | Signed (1 year) | | Tomas Perez | 2B | Signed (minor league deal) | | Miguel Tejada | SS | Traded from BAL | | Oscar Villarreal | RHP | Traded from ATL | | Wesley Wright | LHP | Selected from LA in Rule 5 draft |
| Departed | Pos. | Status | | Matt Albers | RHP | Traded to BAL | | Josh Anderson | OF | Traded to ATL | | Eric Bruntlett | INF | Traded to PHI | | Chris Burke | INF | Traded to ARI | | Michael Costanzo | 3B | Traded to BAL | | Adam Everett | SS | Signed with MIN ($2.8M, 1 year) | | Juan Gutierrez | RHP | Traded to ARI | | Jason Jennings | RHP | Signed with HOU ($4M, 1 year) | | Mike Lamb | INF | Signed with MIN ($6.6M, 2 years) | | Brad Lidge | RHP | Traded to PHI | | Trever Miller | LHP | Signed with TB ($1.6M, 1 year) | | Eric Munson | C | Clamied off waivers by MIL | | Troy Patton | LHP | Traded to BAL | | Chad Qualls | RHP | Traded to ARI | | Dennis Sarfate | RHP | Traded to BAL | | Luke Scott | OF | Traded to BAL |
| Free Agents | Pos. | Status | | Roberto Hernandez | RHP | | | Shea Hillenbrand | INF | | | Mike Lieberthal | C | Retired | | Ramon Martinez | INF | Re-signed (minor league deal) | | Mark Sweeney | INF | Re-signed (1 year) | | Rudy Seanez | RHP | Re-signed ($550K, 1 year) | | David Wells | LHP | |
| Arbitration-Eligible | Pos. | Status | | Joe Beimel | LHP | Re-signed ($1.925M, 1 year) | | Yhency Brazoban | RHP | Re-signed ($540K, 1 year) | | Scott Proctor | RHP | Re-signed ($1.115M, 1 year) | | Jason Repko | OF | Re-signed ($487K, 1 year) |
| Acquired | Pos. | Status | | Danny Ardoin | C | Signed (minor league deal) | | Gary Bennett | C | Signed ($875K, 1 year) | | Angel Chavez | SS | Signed (minor league deal) | | Brian Falkenborg | RHP | Signed (minor league deal) | | John-Ford Griffin | LF | Signed (minor league deal) | | Andruw Jones | CF | Signed ($36.2M, 2 years) | | Greg Jones | RHP | Signed (minor league deal) | | Mike Koplove | RHP | Signed (minor league deal) | | Hiroki Kuroda | RHP | Signed from Japan ($35.5M, 3 years) | | Nook Logan | CF | Signed (minor league deal) | | Tom Martin | LHP | Signed (minor league deal) | | Mike Myers | LHP | Signed (minor league deal) | | Rene Rivera | C | Signed (minor league deal) | | Brian Shackelford | LHP | Signed (minor league deal) | | Tanyon Sturtze | RHP | Signed (minor league deal) | | Terry Tiffee | 3B | Signed (minor league deal) |
| Departed | Pos. | Status | | Luis Gonzalez | OF | Signed with FLA ($2M, 1 year) | | Mark Hendrickson | LHP | Signed with FLA ($1.5M, 1 year) | | Olmedo Saenz | INF | Signed with NYM (minor league deal) | | Chin-hui Tsao | RHP | Signed with KC (minor league deal) | | Randy Wolf | LHP | Signed with SD ($4.75M, 1 year) | | Wesley Wright | LHP | Selected by HOU in Rule 5 draft |
| Free Agents | Pos. | Status | | Tony Graffanino | INF | | | Corey Koskie | 3B | | | Damian Miller | C | |
| Arbitration-Eligible | Pos. | Status | | Dave Bush | RHP | Re-signed (1 year) | | Chris Capuano | LHP | Re-signed ($3.75M, 1 year) | | J.J. Hardy | SS | Re-signed ($2.65M, 1 year) | | Eric Munson | C | Re-signed ($525K, 1 year) | | Brian Shouse | LHP | Re-signed ($2M, 1 year) | | Claudio Vargas | RHP | Re-signed ($3.6M, 1 year) |
| Acquired | Pos. | Status | | Russell Branyan | INF | Signed (minor league deal) | | Mike Cameron | OF | Signed ($7M, 1 year) | | Scott Cassidy | RHP | Retired | | Randy Choate | LHP | Signed (1 year) | | Eric Gagne | RHP | Signed ($10M, 1 year) | | Game Kapler | OF | Signed ($800K, 1 year) | | Jason Kendall | C | Signed ($4.25M, 1 year) | | Guillermo Mota | RHP | Traded from NYM | | Chris Narveson | LHP | Signed (minor league deal) | | Abraham Nunez | 3B | Signed (minor league deal) | | David Riske | RHP | Signed (3 years) | | Salomon Torres | RHP | Traded from PIT |
| Departed | Pos. | Status | | Drew Anderson | 2B | Acquired off waivers by CIN | | Greg Aquino | RHP | Acquired off waivers by BAL | | Francisco Cordero | RHP | Signed with CIN ($46M, 4 years) | | Callix Crabbe | 2B | Selected by SD in Rule 5 draft | | Johnny Estrada | C | Traded to NYM | | Geoff Jenkins | LF | Signed with PHI ($13M, 2 years) | | Ray King | LHP | Signed with WAS (minor league deal) | | Scott Linebrink | RHP | Signed with CHW ($19M, 4 years) | | Kevin Mench | OF | Signed with TEX (minor league deal) | | Kevin Roberts | RHP | Traded to PIT | | Marino Salas | RHP | Traded to PIT | | Matt Wise | RHP | Signed with NYM ($1.2M, 1 year) |
| Free Agents | Pos. | Status | | Marlon Anderson | LF | Re-signed ($2.2M, 2 years) | | Moises Alou | LF | Re-signed ($7.5M option) | | Ramon Castro | C | Re-signed ($4.6M, 2 years) | | Luis Castillo | 2B | Re-signed ($25M, 4 years) | | Jeff Conine | 1B | | | Damion Easley | 2B | Re-signed ($950,000, 1 year) | | Shawn Green | RF | Retired | | Brian Lawrence | RHP | | | Juan Padilla | RHP | Re-signed (minor league deal) | | Aaron Sele | RHP | | | Jose Valentin | 2B | Re-signed (minor league deal) | | David Williams | LHP | |
| Arbitration-Eligible | Pos. | Status | | Endy Chavez | OF | Re-signed ($3.85M, 2 years) | | Ryan Church | OF | Traded from WAS ($2M, 1 year) | | Pedro Feliciano | LHP | Re-signed ($1.025M, 1 year) | | Aaron Heilman | RHP | Re-signed ($1.2M, 1 year) | | Oliver Perez | LHP | Re-signed ($6.5M, 1 year) | | Duaner Sanchez | RHP | Re-signed ($850K, 1 year) | | Jorge Sosa | RHP | Re-signed ($2M, 1 year) |
| Acquired | Pos. | Status | | Tony Armas | RHP | Signed (minor league deal) | | Raul Casanova | C | Signed (minor league deal) | | Ruddy Lugo | RHP | Claimed off waivers from OAK | | Gustavo Molina | C | Signed (minor league deal) | | Olmedo Saenz | INF | Signed (minor league deal) | | Angel Pagan | OF | Traded from CHC | | Steven Register | RHP | Selected from COL in Rule 5 draft | | Ricardo Rincon | LHP | Signed (minor league deal) | | Johan Santana | LHP | Traded from MIN | | Brian Schneider | C | Traded from WAS | | Brian Stokes | RHP | Traded from TB | | Matt Wise | RHP | Signed ($1.2M, 1 year) |
| Departed | Pos. | Status | | Corey Coles | OF | Traded to CHC | | Mike DiFelice | C | Signed with TB (minor league deal) | | Johnny Estrada | C | Signed with WAS ($1.25M, 1 year) | | Tom Glavine | LHP | Signed with ATL ($8M, 1 year) | | Carlos Gomez | OF | Traded to MIN | | Deolis Guerra | RHP | Traded to MIN | | Philip Humber | RHP | Traded to MIN | | Paul Lo Duca | C | Signed with WAS ($5M, 1 year) | | Ryan Meyers | RHP | Traded to CHC | | Kevin Mulvey | RHP | Traded to MIN | | David Newhan | LF | Signed with HOU (minor league deal) | | Lastings Milledge | OF | Traded to WAS | | Guillermo Mota | RHP | Traded to MIL |
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