| Trevor Insley WR, Indianapolis Colts |
| Junior Ioane DE, Oakland Raiders |
| Ken Irvin CB, Buffalo Bills |
| Sedrick Irvin RB, Detroit Lions |
| Heath Irwin G, Miami Dolphins |
| Qadry Ismail WR, Baltimore Ravens |
| Raghib Ismail WR, Dallas Cowboys |
| Steve Israel DB, New Orleans Saints |
| Jabari Issa DE, Arizona Cardinals |
| Chidi Iwuoma DB, Detroit Lions |
| Larry Izzo LB, New England Patriots |